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SRR1336887

GTEX

22f50f1a-6919-5d6f-b765-49a706220c52

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
GTEX
cancer_type_detailed
subtype
cancer_type
GTEX
sex
Male

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

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Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR1443955
brain-umap@2
GTEX0.952
2SRR1486496
brain-umap@2
GTEX0.944
3SJEPD001523_D1.RNA-Seq
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.943
4SRR1370473
brain-umap@2
GTEX0.937
5SRR1457551
brain-umap@2
GTEX0.936
6SRR1500617
brain-umap@2
GTEX0.934
7SRR1432765
brain-umap@2
GTEX0.924
8BS_EXYHZ6D4
brain-umap@2
pilocytic astrocytoma0.923
9SRR1456294
brain-umap@2
GTEX0.922
10SRR662091
brain-umap@2
GTEX0.921

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 17 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
KRAS_SIGNALING_DN0.452Remibrutinib— uncovered
COAGULATION0.333Binimetinib— uncovered
INFLAMMATORY_RESPONSE0.333Idelalisib— uncovered
PANCREAS_BETA_CELLS0.327Cobimetinib— uncovered
ALLOGRAFT_REJECTION0.269Idelalisib— uncovered
EPITHELIAL_MESENCHYMAL_TRANSITION0.220Inavolisib— uncovered
SPERMATOGENESIS0.217Inavolisib— uncovered
XENOBIOTIC_METABOLISM0.179Inavolisib— uncovered
KRAS_SIGNALING_UP0.168Inavolisib— uncovered
IL6_JAK_STAT3_SIGNALING0.122Inavolisib— uncovered
MYOGENESIS0.095Inavolisib— uncovered
BILE_ACID_METABOLISM0.094Inavolisib— uncovered
TNFA_SIGNALING_VIA_NFKB0.065Inavolisib— uncovered
COMPLEMENT0.063Inavolisib— uncovered
ESTROGEN_RESPONSE_LATE0.062Idelalisib— uncovered
ANGIOGENESIS0.049Remibrutinib— uncovered
APICAL_SURFACE0.012Temsirolimus— uncovered