Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

BS_BPWEFR89

Med · Medulloblastoma

459e58d7-1117-5473-a7fd-d1c4b247a461

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
overall_survival_months
58.32000000000001
os_event
true
age_years
10.896
sex
F
race
White
new_clusters
S1
umap1_2d
-0.967982369
umap2_2d
-10.33913848
umap1_3d
-3.629953947
umap2_3d
-0.818947919
umap3_3d
6.453531189
dataset
Med-CBTN

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.420
  • PANCREAS_BETA_CELLS+0.390
  • INTERFERON_ALPHA_RESPONSE+0.360
  • UV_RESPONSE_DN+0.360
  • TNFA_SIGNALING_VIA_NFKB+0.340
  • HYPOXIA+0.320
  • NOTCH_SIGNALING+0.300
  • CHOLESTEROL_HOMEOSTASIS+0.270
  • WNT_BETA_CATENIN_SIGNALING+0.270
  • APICAL_SURFACE+0.260

Top 10 suppressed

  • G2M_CHECKPOINT-0.170
  • SPERMATOGENESIS-0.160
  • PROTEIN_SECRETION-0.140
  • DNA_REPAIR-0.110
  • HEME_METABOLISM-0.110
  • PEROXISOME-0.100
  • E2F_TARGETS-0.060
  • ANGIOGENESIS-0.040
  • PI3K_AKT_MTOR_SIGNALING-0.040
  • TGF_BETA_SIGNALING-0.010

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

6 twins match this tumor's tissue · 4 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1BS_1QXEC43H
medullo-epn-umap@date-based
MedMedulloblastoma0.889
2MDT-AP-0815
medullo-epn-umap@date-based
MedMedulloblastoma0.783
3BS_4T0HPZDC
brain-umap@2
Posterior Fossa Ependymoma0.763
4MDT-AP-2910
medullo-epn-umap@date-based
MedMedulloblastoma0.759
5SJEPD001508_D1.RNA-Seq
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.758
6MDT-AP-0827
medullo-epn-umap@date-based
MedMedulloblastoma0.753
7SJEPD001509_D1.RNA-Seq
medullo-epn-umap@date-based
EPNSupratentorial EPN0.752
8MNG1155
mng-umap@100
0.749
9SRR8518423
breast-umap@18
C0.747
10BS_ZVZDDW2G
brain-umap@2
pleomorphic xanthoastrocytoma(PXA)0.746