Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

MNG987

4c594576-2a0e-5bb1-ba6d-8b44138d98e9

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.523
  • MYC_TARGETS_V1+0.458
  • G2M_CHECKPOINT+0.448
  • INTERFERON_ALPHA_RESPONSE+0.385
  • DNA_REPAIR+0.380
  • MITOTIC_SPINDLE+0.342
  • PROTEIN_SECRETION+0.304
  • BILE_ACID_METABOLISM+0.270
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.236
  • OXIDATIVE_PHOSPHORYLATION+0.202

Top 10 suppressed

  • PANCREAS_BETA_CELLS-0.504
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.418
  • APICAL_SURFACE-0.349
  • ANGIOGENESIS-0.339
  • HEDGEHOG_SIGNALING-0.338
  • COAGULATION-0.336
  • TNFA_SIGNALING_VIA_NFKB-0.328
  • HYPOXIA-0.290
  • TGF_BETA_SIGNALING-0.286
  • MYOGENESIS-0.273

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1BS_EK5PCKY0
brain-umap@2
Supratentorial Ependymoma0.843
2TCGA-58-A46M-01A-11R-A24H-07
lung-landscapes@6
cohortSQ20.828
3MNG274
mng-umap@100
0.826
4R135
bladder-landscape@3
0.819
5TCGA-60-2706-01A-01R-0851-07
lung-landscapes@6
cohortA40.809
604e3aeba-c9bd-483d-9484-5ecc0e64a054
melanoma-umap@29
0.808
7TCGA-18-3419-01A-01R-0980-07
lung-landscapes@6
cohortSQ10.807
8MNG353
mng-umap@100
0.806
9SJEPD030854_D1.RNA-Seq
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.806
10TCGA-58-A46K-01A-11R-A24H-07
lung-landscapes@6
cohortSQ20.804