Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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R181

4ffbfb6d-19b2-58c0-b0d6-566ae4c668ab

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • G2M_CHECKPOINT+0.450
  • E2F_TARGETS+0.390
  • PROTEIN_SECRETION+0.370
  • MYC_TARGETS_V1+0.340
  • ANDROGEN_RESPONSE+0.320
  • UNFOLDED_PROTEIN_RESPONSE+0.260
  • MITOTIC_SPINDLE+0.240
  • OXIDATIVE_PHOSPHORYLATION+0.190
  • MYC_TARGETS_V2+0.170
  • PI3K_AKT_MTOR_SIGNALING+0.170

Top 10 suppressed

  • ANGIOGENESIS-0.460
  • COAGULATION-0.410
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.400
  • HEDGEHOG_SIGNALING-0.370
  • MYOGENESIS-0.340
  • PANCREAS_BETA_CELLS-0.320
  • APICAL_JUNCTION-0.290
  • KRAS_SIGNALING_DN-0.250
  • HYPOXIA-0.240
  • ALLOGRAFT_REJECTION-0.230

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

7 twins match this tumor's tissue · 3 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SJEPD030854_D1.RNA-Seq
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.905
2TCGA-78-7536-01A-11R-2066-07
lung-landscapes@6
cohortA30.904
3R143
bladder-landscape@3
0.889
4MNG1177
mng-umap@100
0.882
5SRR8526729
lung-landscapes@6
cohortSQ10.876
6R128
bladder-landscape@3
0.876
7R361
bladder-landscape@3
0.871
8BS_TV5B86ZD
brain-umap@2
Embryonal tumors0.868
9BS_QXKRN6CR
medullo-epn-umap@date-based
EPNSupratentorial EPN0.866
10MNG33
mng-umap@100
0.861