Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG1117

5a0238f0-d8e7-5851-82f7-c0e669b6dfcd

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V2+0.554
  • OXIDATIVE_PHOSPHORYLATION+0.326
  • UNFOLDED_PROTEIN_RESPONSE+0.290
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.274
  • GLYCOLYSIS+0.272
  • MYC_TARGETS_V1+0.271
  • ANGIOGENESIS+0.270
  • E2F_TARGETS+0.260
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.233
  • DNA_REPAIR+0.229

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.553
  • INTERFERON_GAMMA_RESPONSE-0.504
  • ALLOGRAFT_REJECTION-0.358
  • KRAS_SIGNALING_UP-0.297
  • UV_RESPONSE_DN-0.295
  • TGF_BETA_SIGNALING-0.290
  • IL6_JAK_STAT3_SIGNALING-0.285
  • ANDROGEN_RESPONSE-0.275
  • COMPLEMENT-0.241
  • HEME_METABOLISM-0.228

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG1082
mng-umap@100
0.836
2TCGA-UY-A78M-01A-21R-A352-07
bladder-landscape@3
0.825
3TCGA-66-2781-01A-01R-0851-07
lung-landscapes@6
cohortSQ20.809
4MNG715
mng-umap@100
0.808
5SRR1516100
bladder-landscape@3
0.808
6TCGA-UY-A9PD-01A-11R-A38B-07
bladder-landscape@3
0.802
7MNG1229
mng-umap@100
0.800
8MNG581
mng-umap@100
0.799
9TCGA-E2-A574-01A-11R-A29R-07
breast-umap@18
E0.792
10R97
bladder-landscape@3
0.791