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DRR168604

5b93f7d3-ff6e-53d7-94a1-be2aabf82fff

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
sex
Male

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.450
  • KRAS_SIGNALING_UP+0.430
  • TNFA_SIGNALING_VIA_NFKB+0.430
  • ALLOGRAFT_REJECTION+0.390
  • HEDGEHOG_SIGNALING+0.390
  • INFLAMMATORY_RESPONSE+0.380
  • UV_RESPONSE_DN+0.370
  • IL2_STAT5_SIGNALING+0.350
  • COMPLEMENT+0.340
  • IL6_JAK_STAT3_SIGNALING+0.330

Top 10 suppressed

  • E2F_TARGETS-0.540
  • DNA_REPAIR-0.460
  • G2M_CHECKPOINT-0.440
  • MYC_TARGETS_V2-0.380
  • MYC_TARGETS_V1-0.330
  • MITOTIC_SPINDLE-0.310
  • GLYCOLYSIS-0.290
  • UNFOLDED_PROTEIN_RESPONSE-0.250
  • OXIDATIVE_PHOSPHORYLATION-0.240
  • PI3K_AKT_MTOR_SIGNALING-0.220

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-38-7271-01A-11R-2039-07
lung-landscapes@6
cohortMD20.920
2SRR35579817
breast-umap@18
A0.918
3TCGA-49-6744-01A-11R-1858-07
lung-landscapes@6
cohortA10.918
4TCGA-55-8091-01A-11R-2241-07
lung-landscapes@6
cohortA10.916
5TCGA-38-4626-01A-01R-1206-07
lung-landscapes@6
cohortMD20.915
6TCGA-A2-A0EN-01A-13R-A084-07
breast-umap@18
A0.915
7GSM5359443
bladder-landscape@3
0.913
82eaa09cd-8e3e-4de9-ab96-7a290d780a01
colon-landscapes@1
0.912
9MDT-AP-2743
medullo-epn-umap@date-based
MedMedulloblastoma0.907
10SRR1797302
lung-landscapes@6
cohortMD20.904