MDT-AP-0567
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- overall_survival_months
- 2.04
- age_years
- 13
- sex
- M
- new_clusters
- C4
- umap1_2d
- 4.473487339
- umap2_2d
- 4.190139655
- umap1_3d
- 1.522004643
- umap2_3d
- -1.152388441
- umap3_3d
- -1.77023622
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- EPITHELIAL_MESENCHYMAL_TRANSITION+0.480
- COAGULATION+0.460
- ALLOGRAFT_REJECTION+0.410
- PANCREAS_BETA_CELLS+0.410
- TNFA_SIGNALING_VIA_NFKB+0.400
- MYOGENESIS+0.390
- INFLAMMATORY_RESPONSE+0.380
- IL6_JAK_STAT3_SIGNALING+0.370
- ANGIOGENESIS+0.360
- APICAL_SURFACE+0.360
Top 10 suppressed
- MYC_TARGETS_V1-0.560
- E2F_TARGETS-0.520
- MYC_TARGETS_V2-0.510
- G2M_CHECKPOINT-0.490
- UNFOLDED_PROTEIN_RESPONSE-0.480
- PROTEIN_SECRETION-0.430
- DNA_REPAIR-0.400
- MITOTIC_SPINDLE-0.400
- MTORC1_SIGNALING-0.360
- OXIDATIVE_PHOSPHORYLATION-0.310
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
2 twins match this tumor's tissue · 8 come from a different tissue of origin ← cross-tissue dominant
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | SRR601787 | GTEX | — | 0.951 |
| 2 | ERR2598337 | fetal | fetal | 0.947 |
| 3 | SRR1397906 | GTEX | — | 0.938 |
| 4 | SRR604456 | GTEX | — | 0.937 |
| 5 | SRR1389059 | GTEX | — | 0.937 |
| 6 | BS_YG0A13JH | pilocytic astrocytoma | — | 0.936 |
| 7 | SRR1478946 | GTEX | — | 0.934 |
| 8 | sclcA055A_S52.txt | — | cohortMD2 | 0.932 |
| 9 | c5e09ad2-1f0b-4ea3-9565-a1664f1bb468 | — | — | 0.931 |
| 10 | SRR1335707 | GTEX | — | 0.930 |