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MNG473

7133307f-393a-5611-86b2-0bb0996a1fdc

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V2+0.541
  • E2F_TARGETS+0.504
  • MYC_TARGETS_V1+0.407
  • G2M_CHECKPOINT+0.395
  • CHOLESTEROL_HOMEOSTASIS+0.341
  • MTORC1_SIGNALING+0.273
  • PANCREAS_BETA_CELLS+0.260
  • KRAS_SIGNALING_DN+0.234
  • SPERMATOGENESIS+0.177
  • GLYCOLYSIS+0.148

Top 10 suppressed

  • PROTEIN_SECRETION-0.428
  • INTERFERON_ALPHA_RESPONSE-0.378
  • TGF_BETA_SIGNALING-0.375
  • OXIDATIVE_PHOSPHORYLATION-0.358
  • UV_RESPONSE_DN-0.348
  • ADIPOGENESIS-0.336
  • ALLOGRAFT_REJECTION-0.333
  • IL6_JAK_STAT3_SIGNALING-0.327
  • INTERFERON_GAMMA_RESPONSE-0.326
  • PI3K_AKT_MTOR_SIGNALING-0.317

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

7 twins match this tumor's tissue · 3 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG497
mng-umap@100
0.885
2MNG715
mng-umap@100
0.855
3TCGA-21-1081-01A-01R-0692-07
lung-landscapes@6
cohortSQ10.801
4TCGA-43-A56V-01A-11R-A26W-07
lung-landscapes@6
cohortSQ10.780
5MDT-AP-0426
medullo-epn-umap@date-based
MedMedulloblastoma0.776
6c756a64a-a436-4d25-a9cf-a023b1d8a7a3
melanoma-umap@29
0.773
7ERR2598228
medullo-epn-umap@date-based
fetalfetal0.771
8MNG541
mng-umap@100
0.771
9MNG592
mng-umap@100
0.770
10BS_FKDQJJB5
brain-umap@2
medulloblastoma0.769