Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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98e49cc4-1040-4291-b975-da3e8fc3ddfc

798c4c9d-4447-5c5c-988b-a634ec015f68

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_GAMMA_RESPONSE+0.700
  • ALLOGRAFT_REJECTION+0.600
  • IL6_JAK_STAT3_SIGNALING+0.600
  • INTERFERON_ALPHA_RESPONSE+0.600
  • INFLAMMATORY_RESPONSE+0.500
  • COMPLEMENT+0.400
  • IL2_STAT5_SIGNALING+0.400
  • TNFA_SIGNALING_VIA_NFKB+0.400
  • KRAS_SIGNALING_UP+0.300
  • TGF_BETA_SIGNALING+0.200

Top 10 suppressed

  • MYC_TARGETS_V2-0.700
  • E2F_TARGETS-0.500
  • MYC_TARGETS_V1-0.500
  • OXIDATIVE_PHOSPHORYLATION-0.500
  • ADIPOGENESIS-0.400
  • DNA_REPAIR-0.400
  • G2M_CHECKPOINT-0.400
  • GLYCOLYSIS-0.400
  • MTORC1_SIGNALING-0.300
  • NOTCH_SIGNALING-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-MP-A4TJ-01A-51R-A262-07
lung-landscapes@6
cohortA10.925
22d12ea90-c4f4-4aca-b353-360057b446e2
melanoma-umap@29
0.916
394b2af92-0cfc-40b2-977d-6bd0fa4440d9
melanoma-umap@29
0.910
4DRR168552
bladder-landscape@3
0.904
5d24acd56-d148-487c-8d44-b303a68eb9d2
melanoma-umap@29
0.899
6BS_CS170P7T
brain-umap@2
pilocytic astrocytoma0.895
7SRR2932841
head-neck@1
0.889
8TCGA-55-6971-01A-11R-1949-07
lung-landscapes@6
cohortMD20.889
920030005.Her2HRpos
breast-umap@18
A0.888
10GSM5359418
bladder-landscape@3
0.883