Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR6079990

7b2cd87f-16c0-56a4-9342-30ad480d45c5

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
sex
male

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.550
  • MYC_TARGETS_V1+0.540
  • G2M_CHECKPOINT+0.460
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.380
  • MYC_TARGETS_V2+0.350
  • OXIDATIVE_PHOSPHORYLATION+0.350
  • PROTEIN_SECRETION+0.340
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.310
  • DNA_REPAIR+0.300
  • GLYCOLYSIS+0.280

Top 10 suppressed

  • CHOLESTEROL_HOMEOSTASIS-0.390
  • INTERFERON_ALPHA_RESPONSE-0.330
  • ESTROGEN_RESPONSE_EARLY-0.320
  • KRAS_SIGNALING_DN-0.300
  • INTERFERON_GAMMA_RESPONSE-0.290
  • WNT_BETA_CATENIN_SIGNALING-0.290
  • ESTROGEN_RESPONSE_LATE-0.230
  • ALLOGRAFT_REJECTION-0.200
  • P53_PATHWAY-0.190
  • MYOGENESIS-0.180

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1R265
bladder-landscape@3
0.852
2SRR33532784
breast-umap@18
A0.834
3HLF_LIVER
ccle-hcc@v2024.1
HCC0.821
4R318
bladder-landscape@3
0.812
5SRR4195653
colon-landscapes@1
0.804
6TCGA-CV-7429-01A-11R-2132-07
head-neck@1
0.804
7SJEPD030367_D1.RNA-Seq
medullo-epn-umap@date-based
EPNAnaplastic EPN0.794
8TCGA-21-1071-01A-01R-0692-07
lung-landscapes@6
cohortSQ20.790
9c192c50f-0236-4d28-9343-ce9d9c3ac291
colon-landscapes@1
0.787
10MNG778
mng-umap@100
0.786