Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • COAGULATION+0.400
  • ESTROGEN_RESPONSE_EARLY+0.400
  • ESTROGEN_RESPONSE_LATE+0.400
  • KRAS_SIGNALING_DN+0.400
  • ANGIOGENESIS+0.300
  • APICAL_JUNCTION+0.300
  • APICAL_SURFACE+0.300
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.300
  • MYOGENESIS+0.300
  • XENOBIOTIC_METABOLISM+0.300

Top 10 suppressed

  • E2F_TARGETS-0.600
  • G2M_CHECKPOINT-0.600
  • MYC_TARGETS_V1-0.600
  • PROTEIN_SECRETION-0.600
  • INTERFERON_ALPHA_RESPONSE-0.500
  • MITOTIC_SPINDLE-0.500
  • ANDROGEN_RESPONSE-0.400
  • DNA_REPAIR-0.400
  • INTERFERON_GAMMA_RESPONSE-0.400
  • MTORC1_SIGNALING-0.400

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

6 twins match this tumor's tissue · 4 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
160c210ff-d245-40d2-9de9-7b799cc3ffc9
melanoma-umap@29
0.900
2SRR1405485
brain-umap@2
GTEX0.892
3TCGA-MP-A4TD-01A-32R-A262-07
lung-landscapes@6
cohortA30.890
4R62
bladder-landscape@3
0.887
5R114
bladder-landscape@3
0.880
6SRR1315761
brain-umap@2
GTEX0.868
7TCGA-KQ-A41P-01A-12R-A33J-07
bladder-landscape@3
0.867
8SRR1499193
brain-umap@2
GTEX0.866
957583139-d2d3-4b97-a616-aa96058d4682
melanoma-umap@29
0.864
10SRR1437555
brain-umap@2
GTEX0.863