Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

SRR25617891

· E

7c7e82b6-a161-5f4b-a7df-81890075191f

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
E
subtype
E

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.530
  • TGF_BETA_SIGNALING+0.480
  • ANGIOGENESIS+0.430
  • NOTCH_SIGNALING+0.340
  • PROTEIN_SECRETION+0.320
  • G2M_CHECKPOINT+0.310
  • HYPOXIA+0.310
  • MTORC1_SIGNALING+0.310
  • MYC_TARGETS_V1+0.310
  • E2F_TARGETS+0.300

Top 10 suppressed

  • PEROXISOME-0.300
  • ALLOGRAFT_REJECTION-0.290
  • ESTROGEN_RESPONSE_EARLY-0.270
  • DNA_REPAIR-0.260
  • PANCREAS_BETA_CELLS-0.180
  • FATTY_ACID_METABOLISM-0.160
  • ESTROGEN_RESPONSE_LATE-0.140
  • KRAS_SIGNALING_DN-0.140
  • COMPLEMENT-0.120
  • IL6_JAK_STAT3_SIGNALING-0.120

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR25617936
breast-umap@18
E0.809
2TCGA-55-6975-01A-11R-1949-07
lung-landscapes@6
cohortA40.772
3MNG56
mng-umap@100
0.744
4TCGA-A7-A13D-01A-13R-A277-07
breast-umap@18
E0.741
5TCGA-60-2703-01A-11R-2045-07
lung-landscapes@6
cohortSQ10.734
65472fa65-a8e2-4593-abd8-e241d1bdec84
colon-landscapes@1
0.722
720110025.TNBC
breast-umap@18
E0.716
8TCGA-A7-A13D-01A-13R-A12P-07
breast-umap@18
E0.711
9TCGA-BH-A0WA-01A-11R-A109-07
breast-umap@18
E0.702
10SRR12696773
melanoma-umap@29
0.701