Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR8518245

· F

8afac9ab-7bf3-5e01-9ce0-fbe2ce6167e2

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
F
subtype
F

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • OXIDATIVE_PHOSPHORYLATION+0.430
  • FATTY_ACID_METABOLISM+0.410
  • GLYCOLYSIS+0.390
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.370
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.360
  • MTORC1_SIGNALING+0.330
  • HYPOXIA+0.320
  • ADIPOGENESIS+0.310
  • CHOLESTEROL_HOMEOSTASIS+0.250
  • PROTEIN_SECRETION+0.250

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.540
  • INTERFERON_GAMMA_RESPONSE-0.520
  • ALLOGRAFT_REJECTION-0.500
  • IL6_JAK_STAT3_SIGNALING-0.410
  • INFLAMMATORY_RESPONSE-0.330
  • WNT_BETA_CATENIN_SIGNALING-0.320
  • MYC_TARGETS_V2-0.290
  • TNFA_SIGNALING_VIA_NFKB-0.280
  • COMPLEMENT-0.250
  • APICAL_SURFACE-0.190

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR8518241
breast-umap@18
F0.879
2SRR8518414
breast-umap@18
C0.850
3C3L-01632
lung-landscapes@6
cohortA40.824
4MNG1099
mng-umap@100
0.800
5TCGA-E2-A1LB-01A-11R-A144-07
breast-umap@18
F0.799
6SRR8518380
breast-umap@18
C0.793
7TCGA-CV-6935-01A-11R-1915-07
head-neck@1
0.785
8TCGA-AQ-A04L-01B-21R-A10J-07
breast-umap@18
C0.781
9SRR8518157
breast-umap@18
F0.777
10SRR1313112
breast-umap@18
B0.769