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TCGA-CQ-6225-01A-11R-1915-07

a394eeb5-d9f7-59e7-8a37-4076ccb05f0b

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
overall_survival_months
0.092009132
sex
male

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

No GSVA scores available for this sample.

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR12475110
colon-landscapes@1
0.943
2TCGA-BB-8601-01A-11R-2403-07
head-neck@1
0.940
320110070.TNBC
breast-umap@18
E0.932
4TCGA-63-A5MY-01A-11R-A26W-07
lung-landscapes@6
cohortSQ20.926
563bab58e-1dfd-43df-8188-4b8d766913f3
colon-landscapes@1
0.925
6ERR2278860
head-neck@1
0.922
7513fb61a-1339-45d2-8963-6337e3aff5df
colon-landscapes@1
0.921
8TCGA-85-8070-01A-11R-2247-07
lung-landscapes@6
cohortSQ20.915
9ERR2278847
head-neck@1
0.911
10TCGA-33-4532-01A-01R-1201-07
lung-landscapes@6
cohortSQ20.911

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 17 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
OXIDATIVE_PHOSPHORYLATION0.480Remibrutinib— uncovered
MYC_TARGETS_V10.470Inavolisib— uncovered
MYC_TARGETS_V20.410Idelalisib— uncovered
DNA_REPAIR0.310Idelalisib— uncovered
MTORC1_SIGNALING0.270Inavolisib— uncovered
FATTY_ACID_METABOLISM0.260Inavolisib— uncovered
E2F_TARGETS0.200Inavolisib— uncovered
REACTIVE_OXYGEN_SPECIES_PATHWAY0.190Inavolisib— uncovered
GLYCOLYSIS0.180Inavolisib— uncovered
ADIPOGENESIS0.160Inavolisib— uncovered
G2M_CHECKPOINT0.160Inavolisib— uncovered
CHOLESTEROL_HOMEOSTASIS0.150Remibrutinib— uncovered
SPERMATOGENESIS0.120Inavolisib— uncovered
UNFOLDED_PROTEIN_RESPONSE0.110Idelalisib— uncovered
PEROXISOME0.070Idelalisib— uncovered
KRAS_SIGNALING_DN0.050Remibrutinib— uncovered
P53_PATHWAY0.030Idelalisib— uncovered