Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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311f1988-e21e-4130-b944-2a34d7d46d28

b44f4ffb-91a5-5d5a-a18b-1f4cdc88a3ec

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • ALLOGRAFT_REJECTION+0.600
  • IL6_JAK_STAT3_SIGNALING+0.600
  • INTERFERON_ALPHA_RESPONSE+0.600
  • INTERFERON_GAMMA_RESPONSE+0.600
  • INFLAMMATORY_RESPONSE+0.500
  • COMPLEMENT+0.400
  • IL2_STAT5_SIGNALING+0.400
  • PANCREAS_BETA_CELLS+0.400
  • APOPTOSIS+0.300
  • COAGULATION+0.300

Top 10 suppressed

  • MYC_TARGETS_V2-0.600
  • DNA_REPAIR-0.400
  • E2F_TARGETS-0.400
  • G2M_CHECKPOINT-0.300
  • MYC_TARGETS_V1-0.300
  • OXIDATIVE_PHOSPHORYLATION-0.300
  • UNFOLDED_PROTEIN_RESPONSE-0.200
  • WNT_BETA_CATENIN_SIGNALING-0.200
  • MYOGENESIS-0.100
  • P53_PATHWAY-0.100

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

7 twins match this tumor's tissue · 3 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1bd09bf00-3fb3-41fc-ae4d-4ac68a925a6b
melanoma-umap@29
0.898
22833b2f4-e943-4570-96c2-a42c127cd1fa
melanoma-umap@29
0.889
3TCGA-CN-5369-01A-01R-1436-07
head-neck@1
0.886
4BS_02NZT8CE
brain-umap@2
low-grade glioma0.886
5BS_699TN5RN
brain-umap@2
Ganglioglioma0.875
674cffe84-dca8-4673-925a-9e0d6344832a
melanoma-umap@29
0.874
7ERR2208891
melanoma-umap@29
0.873
8BS_C6SKJG3N
brain-umap@2
pilocytic astrocytoma0.872
9TCGA-AC-A2FB-01A-11R-A17B-07
breast-umap@18
A0.862
10R323
bladder-landscape@3
0.861