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ERR2278875

b7d8d7ca-1077-5cce-9339-a638c2380d3d

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.570
  • TNFA_SIGNALING_VIA_NFKB+0.570
  • ANGIOGENESIS+0.560
  • INFLAMMATORY_RESPONSE+0.500
  • IL6_JAK_STAT3_SIGNALING+0.480
  • HEDGEHOG_SIGNALING+0.400
  • IL2_STAT5_SIGNALING+0.400
  • KRAS_SIGNALING_UP+0.370
  • ALLOGRAFT_REJECTION+0.330
  • COMPLEMENT+0.330

Top 10 suppressed

  • OXIDATIVE_PHOSPHORYLATION-0.520
  • ADIPOGENESIS-0.300
  • FATTY_ACID_METABOLISM-0.280
  • BILE_ACID_METABOLISM-0.250
  • PROTEIN_SECRETION-0.190
  • HEME_METABOLISM-0.180
  • PEROXISOME-0.160
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.160
  • P53_PATHWAY-0.130
  • DNA_REPAIR-0.100

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-56-8503-01A-11R-2403-07
lung-landscapes@6
cohortSQ10.914
2TCGA-BT-A3PK-01A-21R-A220-07
bladder-landscape@3
0.906
3SRR4296104
lung-landscapes@6
cohortA10.886
420050166.TNBC
breast-umap@18
D0.881
5TCGA-FD-A3B7-01A-31R-A20F-07
bladder-landscape@3
0.879
6TCGA-OR-A5J8-01
acc-tcga-pancan-2018@2018
Adrenocortical CarcinomaAdrenocortical Carcinoma, Usual Type0.866
7BS_NR3P3GN2
brain-umap@2
high-grade glioma0.866
8R385
bladder-landscape@3
0.852
9c56e13bb-f1b0-4ee3-85c1-807c7c3bcef9
colon-landscapes@1
0.852
10TCGA-85-8582-01A-21R-2403-07
lung-landscapes@6
cohortSQ10.844