Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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GSM6454747

· F

bae1c2c6-dec6-5f18-ab06-f309d257df7e

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
F
subtype
F

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • ANDROGEN_RESPONSE+0.470
  • PROTEIN_SECRETION+0.440
  • UV_RESPONSE_DN+0.410
  • XENOBIOTIC_METABOLISM+0.370
  • ADIPOGENESIS+0.350
  • BILE_ACID_METABOLISM+0.340
  • FATTY_ACID_METABOLISM+0.330
  • KRAS_SIGNALING_UP+0.330
  • PEROXISOME+0.310
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.260

Top 10 suppressed

  • MYC_TARGETS_V2-0.580
  • E2F_TARGETS-0.520
  • INTERFERON_ALPHA_RESPONSE-0.480
  • WNT_BETA_CATENIN_SIGNALING-0.470
  • G2M_CHECKPOINT-0.450
  • MYC_TARGETS_V1-0.380
  • INTERFERON_GAMMA_RESPONSE-0.280
  • KRAS_SIGNALING_DN-0.250
  • UV_RESPONSE_UP-0.250
  • HEDGEHOG_SIGNALING-0.240

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR8518149
breast-umap@18
F0.844
2SRR8518177
breast-umap@18
F0.830
3SRR8518325
breast-umap@18
F0.814
4SRR8613737
breast-umap@18
F0.806
5SRR8613755
breast-umap@18
F0.796
6SRR4195645
colon-landscapes@1
0.779
7SRR8518315
breast-umap@18
F0.771
8SRR8518401
breast-umap@18
F0.767
9SRR35579842
breast-umap@18
A0.762
105c3c4b79-0682-4f19-96aa-071316a354d4
colon-landscapes@1
0.760