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MNG387

befe0ff2-4b7a-523a-9210-5a1750bcb7b9

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.494
  • G2M_CHECKPOINT+0.476
  • MYC_TARGETS_V1+0.468
  • MYC_TARGETS_V2+0.399
  • MITOTIC_SPINDLE+0.319
  • UNFOLDED_PROTEIN_RESPONSE+0.311
  • MTORC1_SIGNALING+0.305
  • INTERFERON_ALPHA_RESPONSE+0.287
  • WNT_BETA_CATENIN_SIGNALING+0.285
  • DNA_REPAIR+0.217

Top 10 suppressed

  • MYOGENESIS-0.264
  • ALLOGRAFT_REJECTION-0.207
  • BILE_ACID_METABOLISM-0.204
  • COAGULATION-0.200
  • IL6_JAK_STAT3_SIGNALING-0.193
  • HEME_METABOLISM-0.183
  • TGF_BETA_SIGNALING-0.170
  • KRAS_SIGNALING_UP-0.158
  • TNFA_SIGNALING_VIA_NFKB-0.148
  • APOPTOSIS-0.136

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG979
mng-umap@100
0.847
2BS_P7EY9DXG
brain-umap@2
ATRT0.833
3MBCProject_1160_T2_RNA
breast-umap@18
E0.820
4E0DE33EA-C3DF-478E-9C4D-86E3C7B3A1D9
brain-umap@2
0.818
5TCGA-77-8009-01A-11R-2187-07
lung-landscapes@6
cohortSQ20.815
69970B75F-7AC6-431B-BDBB-120D01582CBE
brain-umap@2
0.809
7MNG163
mng-umap@100
0.807
8TCGA-91-6836-01A-21R-1858-07
lung-landscapes@6
cohortA10.801
9BS_B1C6GZ84
brain-umap@2
Diffuse intrinsic pontine glioma0.800
10592CC5DC-4DB7-4961-AB2B-89C8FE4A83D3
brain-umap@2
0.797