Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MITOTIC_SPINDLE+0.400
  • MYC_TARGETS_V1+0.400
  • MYC_TARGETS_V2+0.400
  • E2F_TARGETS+0.300
  • G2M_CHECKPOINT+0.300
  • PROTEIN_SECRETION+0.300
  • DNA_REPAIR+0.200
  • UV_RESPONSE_DN+0.200
  • ANDROGEN_RESPONSE+0.100
  • PI3K_AKT_MTOR_SIGNALING+0.100

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.600
  • IL6_JAK_STAT3_SIGNALING-0.600
  • INTERFERON_GAMMA_RESPONSE-0.600
  • INFLAMMATORY_RESPONSE-0.500
  • INTERFERON_ALPHA_RESPONSE-0.500
  • COMPLEMENT-0.400
  • KRAS_SIGNALING_UP-0.400
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.400
  • TNFA_SIGNALING_VIA_NFKB-0.400
  • XENOBIOTIC_METABOLISM-0.400

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-O2-A5IB-01A-11R-A27Q-07
lung-landscapes@6
cohortMD10.909
2TCGA-91-6847-01A-11R-1949-07
lung-landscapes@6
cohortMD10.904
3TCGA-33-4587-01A-11R-2125-07
lung-landscapes@6
cohortMD10.901
4TCGA-78-7155-01A-11R-2039-07
lung-landscapes@6
cohortMD10.898
5s0122172
melanoma-umap@29
0.898
6SRR9879265
lung-landscapes@6
cohortMD10.891
7TCGA-77-A5G6-01A-11R-A27Q-07
lung-landscapes@6
cohortSQ10.888
820120131.TNBC
breast-umap@18
E0.885
9SJEPD031150_D1.RNA-Seq
medullo-epn-umap@date-based
EPNEPN Tumor0.884
10TCGA-A8-A0AB-01A-11R-A034-07
breast-umap@18
B0.884