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MDT-AP-3297

Med · Medulloblastoma

cf5bd321-0dc9-50bf-97ce-d3ac63d9aae6

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
age_years
5.9
sex
M
new_clusters
C1
umap1_2d
4.003953241
umap2_2d
-0.808501722
umap1_3d
-0.518166039
umap2_3d
-4.007075522
umap3_3d
-0.295395054
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.660
  • G2M_CHECKPOINT+0.660
  • MYC_TARGETS_V1+0.550
  • MITOTIC_SPINDLE+0.470
  • TGF_BETA_SIGNALING+0.420
  • MTORC1_SIGNALING+0.410
  • MYC_TARGETS_V2+0.410
  • UNFOLDED_PROTEIN_RESPONSE+0.340
  • DNA_REPAIR+0.320
  • ANDROGEN_RESPONSE+0.290

Top 10 suppressed

  • PANCREAS_BETA_CELLS-0.460
  • MYOGENESIS-0.410
  • COAGULATION-0.400
  • HEDGEHOG_SIGNALING-0.400
  • INTERFERON_ALPHA_RESPONSE-0.400
  • ALLOGRAFT_REJECTION-0.390
  • IL6_JAK_STAT3_SIGNALING-0.370
  • INFLAMMATORY_RESPONSE-0.370
  • COMPLEMENT-0.350
  • HYPOXIA-0.340

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-2497
medullo-epn-umap@date-based
MedMedulloblastoma0.962
2MDT-AP-0167
medullo-epn-umap@date-based
MedMedulloblastoma0.939
3R143
bladder-landscape@3
0.921
4MDT-AP-3357
medullo-epn-umap@date-based
MedMedulloblastoma0.919
5C6A16A8F-0AB7-42E9-A068-15EECF2912D3
brain-umap@2
0.900
6MDT-AP-0164
medullo-epn-umap@date-based
MedMedulloblastoma0.896
7BS_G23JJAZY
medullo-epn-umap@date-based
EPNSupratentorial EPN0.887
8MDT-AP-3307
medullo-epn-umap@date-based
MedMedulloblastoma0.884
9MDT-AP-2085
medullo-epn-umap@date-based
MedMedulloblastoma0.881
10MNG753
mng-umap@100
0.880