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SJEPD001501_D1.RNA-Seq

EPN · Supratentorial EPN

da8b13b3-50c9-5805-971a-ccf04fb6592f

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
EPN
cancer_type_detailed
subtype
Supratentorial EPN
cancer_type
EPN
subtype
Supratentorial EPN
fusion
ZFTA_RELA
e1_e2
E1
umap1_2d
-2.539706289
umap2_2d
0.589560865
umap1_3d
0.94880807
umap2_3d
3.236779941
umap3_3d
-2.780332614
dataset
EPN-StJude

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • WNT_BETA_CATENIN_SIGNALING+0.490
  • TNFA_SIGNALING_VIA_NFKB+0.420
  • UV_RESPONSE_UP+0.360
  • TGF_BETA_SIGNALING+0.310
  • APICAL_SURFACE+0.260
  • INTERFERON_ALPHA_RESPONSE+0.230
  • PI3K_AKT_MTOR_SIGNALING+0.220
  • CHOLESTEROL_HOMEOSTASIS+0.190
  • INFLAMMATORY_RESPONSE+0.190
  • P53_PATHWAY+0.190

Top 10 suppressed

  • OXIDATIVE_PHOSPHORYLATION-0.370
  • E2F_TARGETS-0.260
  • G2M_CHECKPOINT-0.240
  • SPERMATOGENESIS-0.190
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.150
  • MITOTIC_SPINDLE-0.140
  • COMPLEMENT-0.120
  • UV_RESPONSE_DN-0.120
  • PROTEIN_SECRETION-0.100
  • ADIPOGENESIS-0.080

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG1254
mng-umap@100
0.686
2SRR8942960
bladder-landscape@3
0.674
3TCGA-B6-A0WY-01A-11R-A109-07
breast-umap@18
A0.655
4BS_CXVJK2FY
brain-umap@2
Supratentorial Ependymoma0.654
5SJEPD001541_D1.RNA-Seq
medullo-epn-umap@date-based
EPNSupratentorial EPN0.638
6SJEPD001535_R1.RNA-Seq
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.632
7SAMN03290922
melanoma-umap@29
0.629
8SJEPD034_D.RNA-Seq
medullo-epn-umap@date-based
EPNSupratentorial EPN0.629
9MNG399
mng-umap@100
0.624
10BS_CXVJK2FY
medullo-epn-umap@date-based
EPNSupratentorial EPN0.623