Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR12202472

dbadacf8-4627-5a08-aa39-d57dbb9562ca

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • PROTEIN_SECRETION+0.450
  • OXIDATIVE_PHOSPHORYLATION+0.420
  • MYC_TARGETS_V1+0.400
  • NOTCH_SIGNALING+0.380
  • TGF_BETA_SIGNALING+0.340
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.330
  • PI3K_AKT_MTOR_SIGNALING+0.280
  • MTORC1_SIGNALING+0.270
  • ADIPOGENESIS+0.240
  • MITOTIC_SPINDLE+0.240

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.600
  • INTERFERON_GAMMA_RESPONSE-0.490
  • IL6_JAK_STAT3_SIGNALING-0.360
  • ALLOGRAFT_REJECTION-0.310
  • HEDGEHOG_SIGNALING-0.230
  • INFLAMMATORY_RESPONSE-0.220
  • XENOBIOTIC_METABOLISM-0.180
  • KRAS_SIGNALING_DN-0.170
  • BILE_ACID_METABOLISM-0.140
  • CHOLESTEROL_HOMEOSTASIS-0.120

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1R205
bladder-landscape@3
0.803
2R266
bladder-landscape@3
0.799
3SRR12202463
bladder-landscape@3
0.791
4TCGA-75-7027-01A-11R-1949-07
lung-landscapes@6
cohortA40.781
5MNG1017
mng-umap@100
0.766
6s0112297
melanoma-umap@29
0.759
7TCGA-C8-A137-01A-11R-A115-07
breast-umap@18
C0.752
8TCGA-AC-A23H-01A-11R-A157-07
breast-umap@18
C0.752
9SRR650181
bladder-landscape@3
0.752
10SRR13311164
bladder-landscape@3
0.748