Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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ddf9957c-3b4f-5570-b9a6-fc6cb4620981

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
age_years
69

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.690
  • TNFA_SIGNALING_VIA_NFKB+0.610
  • APICAL_SURFACE+0.540
  • TGF_BETA_SIGNALING+0.540
  • ANGIOGENESIS+0.530
  • INFLAMMATORY_RESPONSE+0.480
  • UV_RESPONSE_DN+0.460
  • IL6_JAK_STAT3_SIGNALING+0.440
  • APICAL_JUNCTION+0.430
  • KRAS_SIGNALING_UP+0.400

Top 10 suppressed

  • MYC_TARGETS_V2-0.730
  • MYC_TARGETS_V1-0.640
  • E2F_TARGETS-0.610
  • OXIDATIVE_PHOSPHORYLATION-0.610
  • G2M_CHECKPOINT-0.500
  • FATTY_ACID_METABOLISM-0.440
  • DNA_REPAIR-0.380
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.370
  • PEROXISOME-0.350
  • MTORC1_SIGNALING-0.310

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
167ed15bc-bbe5-4da7-81f9-002c54483f67
colon-landscapes@1
0.959
24f709f4b-3140-47be-b55a-7713062545e9
colon-landscapes@1
0.944
3f22cfa82-a346-4fed-bc81-21a29bf990ee
colon-landscapes@1
0.943
421196229-e39e-4846-be58-a1055b3ae50e
colon-landscapes@1
0.940
54925248f-21e2-476e-937c-02e0a748c77b
colon-landscapes@1
0.938
6ERR2208918
melanoma-umap@29
0.934
71b5aacb8-0e2e-4888-bc61-48c4aa4d4684
colon-landscapes@1
0.932
8TCGA-CX-7085-01A-21R-2016-07
head-neck@1
0.931
92cec663c-00c8-48b5-967b-f2a53c0fb409
colon-landscapes@1
0.931
10cadbc884-10b6-41e4-8aee-dc11a1453b8c
colon-landscapes@1
0.926