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SRR1472663

GTEX

ec8a1594-40b7-5aff-b4e8-4ba54fb04b02

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
GTEX
cancer_type_detailed
subtype
cancer_type
GTEX
sex
Male

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

No GSVA scores available for this sample.

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR1488651
brain-umap@2
GTEX0.969
2SRR1451964
brain-umap@2
GTEX0.965
3SRR1479759
brain-umap@2
GTEX0.961
4SRR1330675
brain-umap@2
GTEX0.960
5BS_EXYHZ6D4
brain-umap@2
pilocytic astrocytoma0.959
6SRR1474886
brain-umap@2
GTEX0.958
7SRR1446287
brain-umap@2
GTEX0.957
8SRR1340301
brain-umap@2
GTEX0.955
9SRR1336006
brain-umap@2
GTEX0.954
10SRR662091
brain-umap@2
GTEX0.953

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 15 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
KRAS_SIGNALING_DN0.484Remibrutinib— uncovered
PANCREAS_BETA_CELLS0.317Cobimetinib— uncovered
MYOGENESIS0.266Inavolisib— uncovered
EPITHELIAL_MESENCHYMAL_TRANSITION0.235Inavolisib— uncovered
SPERMATOGENESIS0.226Inavolisib— uncovered
COAGULATION0.223Binimetinib— uncovered
ESTROGEN_RESPONSE_LATE0.160Idelalisib— uncovered
XENOBIOTIC_METABOLISM0.127Inavolisib— uncovered
BILE_ACID_METABOLISM0.104Inavolisib— uncovered
ESTROGEN_RESPONSE_EARLY0.076Inavolisib— uncovered
ALLOGRAFT_REJECTION0.071Idelalisib— uncovered
APICAL_SURFACE0.069Temsirolimus— uncovered
HEDGEHOG_SIGNALING0.058Inavolisib— uncovered
INFLAMMATORY_RESPONSE0.010Idelalisib— uncovered
KRAS_SIGNALING_UP0.007Inavolisib— uncovered