Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
age_years
70.2505133470226

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYOGENESIS+0.440
  • BILE_ACID_METABOLISM+0.380
  • UV_RESPONSE_DN+0.380
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.370
  • APICAL_JUNCTION+0.310
  • HEDGEHOG_SIGNALING+0.280
  • ESTROGEN_RESPONSE_EARLY+0.250
  • ANDROGEN_RESPONSE+0.220
  • KRAS_SIGNALING_UP+0.220
  • ADIPOGENESIS+0.190

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.520
  • INTERFERON_GAMMA_RESPONSE-0.480
  • E2F_TARGETS-0.430
  • G2M_CHECKPOINT-0.380
  • DNA_REPAIR-0.330
  • MYC_TARGETS_V1-0.290
  • ALLOGRAFT_REJECTION-0.270
  • IL6_JAK_STAT3_SIGNALING-0.270
  • OXIDATIVE_PHOSPHORYLATION-0.250
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.230

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR35579814
breast-umap@18
A0.822
220040084.LumA
breast-umap@18
A0.818
3TCGA-HN-A2OB-01A-21R-A27Q-07
breast-umap@18
A0.811
4ERR2208930
melanoma-umap@29
0.806
5SRR8613781
breast-umap@18
A0.803
6TCGA-K4-AAQO-01A-11R-A38B-07
bladder-landscape@3
0.800
7ULC0515T_S15
lung-landscapes@6
cohortA10.796
820060260.Her2HRpos
breast-umap@18
A0.796
9s0095156
melanoma-umap@29
0.794
10BSR_18_0092_S48
breast-umap@18
A0.792