Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • ANGIOGENESIS+0.400
  • APICAL_SURFACE+0.400
  • COAGULATION+0.400
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.400
  • KRAS_SIGNALING_DN+0.300
  • MYOGENESIS+0.300
  • NOTCH_SIGNALING+0.300
  • APICAL_JUNCTION+0.200
  • CHOLESTEROL_HOMEOSTASIS+0.200
  • PANCREAS_BETA_CELLS+0.200

Top 10 suppressed

  • PROTEIN_SECRETION-0.500
  • G2M_CHECKPOINT-0.400
  • MITOTIC_SPINDLE-0.400
  • MYC_TARGETS_V1-0.400
  • UNFOLDED_PROTEIN_RESPONSE-0.400
  • ANDROGEN_RESPONSE-0.300
  • E2F_TARGETS-0.300
  • MTORC1_SIGNALING-0.300
  • OXIDATIVE_PHOSPHORYLATION-0.300
  • PI3K_AKT_MTOR_SIGNALING-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1R81
bladder-landscape@3
0.894
2TCGA-XF-A9SP-01A-11R-A39I-07
bladder-landscape@3
0.861
3TCGA-MP-A4TD-01A-32R-A262-07
lung-landscapes@6
cohortA30.853
412305e97-f72f-4de7-9735-4cdbecb60296
melanoma-umap@29
0.850
5SAMN03290910
melanoma-umap@29
0.848
6SRR8943033
bladder-landscape@3
0.833
7SRR493947
lung-landscapes@6
cohortA10.831
8a6b176e9-f4fc-4188-9771-ab2f3e00a4a8
colon-landscapes@1
0.826
969d9a82b-5c37-45bd-a1cf-ffe1392e84fc
melanoma-umap@29
0.823
10TCGA-FD-A43U-01A-11R-A23W-07
bladder-landscape@3
0.818