Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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1c7309b2-91f0-4305-aad7-f86c0d143559

f8226674-a55e-54f5-b583-190a3621e786

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.500
  • G2M_CHECKPOINT+0.500
  • DNA_REPAIR+0.400
  • MYC_TARGETS_V1+0.400
  • MYC_TARGETS_V2+0.400
  • OXIDATIVE_PHOSPHORYLATION+0.400
  • PI3K_AKT_MTOR_SIGNALING+0.400
  • INTERFERON_ALPHA_RESPONSE+0.300
  • MTORC1_SIGNALING+0.300
  • UNFOLDED_PROTEIN_RESPONSE+0.300

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.400
  • COAGULATION-0.400
  • BILE_ACID_METABOLISM-0.300
  • COMPLEMENT-0.300
  • INFLAMMATORY_RESPONSE-0.300
  • KRAS_SIGNALING_UP-0.300
  • ANGIOGENESIS-0.200
  • APICAL_JUNCTION-0.200
  • APICAL_SURFACE-0.200
  • ESTROGEN_RESPONSE_EARLY-0.200

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG979
mng-umap@100
0.830
294F9B9B1-A23E-4947-BD09-67CBA3052C51
brain-umap@2
0.823
3EE4F9349-F750-4471-BFE7-7230784569E1
brain-umap@2
0.822
4aMVAC.P_011_TURBT_S228
bladder-landscape@3
0.811
5SRR934990
brain-umap@2
0.804
63E5F6B52-112E-4F87-B49C-061B9DFD1E2D
brain-umap@2
0.796
7E0DE33EA-C3DF-478E-9C4D-86E3C7B3A1D9
brain-umap@2
0.796
8TCGA-91-6836-01A-21R-1858-07
lung-landscapes@6
cohortA10.794
9TCGA-77-8009-01A-11R-2187-07
lung-landscapes@6
cohortSQ20.792
108BC036E8-0EA0-4346-A551-2A5F8975FEAB
brain-umap@2
0.788