Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Apatinib

2820ecbd-c6e3-53d6-875e-b61593f6429f · NMPA Approved · targets KDR_VEGFR2

Apatinib

MeasuredReference

Apatinib targets RAF1, C_KIT, CSF1R. Strongest hallmark effect: tumor promoting inflammation.

Primary targets

RAF1C_KITCSF1RFLT1_VEGFR1YSK4_MAP3K19

Top hallmarks

  • tumor promoting inflammation3.4k
  • proliferation2.2k
  • immune evasion2.0k

Top pathways disrupted

No pathway data.

Resistance landscape — Apatinib

MeasuredReference

1 known oncogenic variants exist on Apatinib's top targets — see detail for inhibition impact.

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