Ceritinib — dose-response

MeasuredDerived

Dose-response curves across the assayed kinome. ← All drugs

Ceritinib × IKBKE

MeasuredDerived

IC50

18.85 nM

Hill slope

0.27

R²

0.0820

Top kinases by potency

MeasuredDerived

Ordered by IC50 ascending (fitted).

Kinase	IC50
CSNK2A1	0.26 nM
CDK9+CCNT2	0.28 nM
CDK3+CCNE1	0.30 nM
NEK7	0.32 nM
PLK3	0.56 nM
MAPK12	0.74 nM
ROS1	0.75 nM
ALK	1.69 nM
BMPR2	2.00 nM
CDC7	2.14 nM
RIPK2	2.23 nM
ACVR1B	2.31 nM
WEE1	2.34 nM
MAPKAPK2	2.41 nM
PDPK1	2.43 nM
MAP3K3	2.72 nM
FES	3.21 nM
LRRK2	3.79 nM
BMX	4.10 nM
AKT3	4.22 nM
IGF1R	4.99 nM
PAK3	5.91 nM
MAPKAPK3	7.00 nM
TSSK1B	7.40 nM
CDK2+CCNA2	8.72 nM
TYRO3	10.84 nM
PTK2	11.28 nM
CIT	15.13 nM
TNK1	18.06 nM
IKBKE	18.85 nM