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MDT-AP-1122

Med · Medulloblastoma

04ba3b07-e897-5dfa-939c-7bf8728d37f3

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
overall_survival_months
16.799999999999997
os_event
false
age_years
6
sex
M
new_clusters
C6
umap1_2d
3.667907682
umap2_2d
7.081646727
umap1_3d
2.495809007
umap2_3d
-0.419305369
umap3_3d
-4.813405168
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • OXIDATIVE_PHOSPHORYLATION+0.390
  • DNA_REPAIR+0.380
  • UNFOLDED_PROTEIN_RESPONSE+0.380
  • G2M_CHECKPOINT+0.310
  • PROTEIN_SECRETION+0.310
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.300
  • MITOTIC_SPINDLE+0.290
  • E2F_TARGETS+0.260
  • FATTY_ACID_METABOLISM+0.250
  • MYC_TARGETS_V1+0.250

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.480
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.440
  • INFLAMMATORY_RESPONSE-0.400
  • TNFA_SIGNALING_VIA_NFKB-0.380
  • APICAL_SURFACE-0.360
  • COAGULATION-0.350
  • IL6_JAK_STAT3_SIGNALING-0.300
  • IL2_STAT5_SIGNALING-0.260
  • KRAS_SIGNALING_UP-0.260
  • ANGIOGENESIS-0.250

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

5 twins match this tumor's tissue · 5 come from a different tissue of origin ← cross-tissue dominant

#SampleCancer typeSubtypecos similarity
1MDT-AP-1214
medullo-epn-umap@date-based
MedMedulloblastoma0.888
2BS_QXKRN6CR
medullo-epn-umap@date-based
EPNSupratentorial EPN0.868
3BS_KSKZ9J7J
brain-umap@2
Embryonal tumors0.863
4BS_QXKRN6CR
brain-umap@2
Supratentorial Ependymoma0.857
5BS_7G42J2SK
brain-umap@2
Supratentorial Ependymoma0.856
6BS_BSV07M7Z
medullo-epn-umap@date-based
MedMedulloblastoma0.854
7TCGA-58-A46K-01A-11R-A24H-07
lung-landscapes@6
cohortSQ20.852
8BS_H4NXBD2D
brain-umap@2
Supratentorial Ependymoma0.837
9SAMN03290941
melanoma-umap@29
0.828
10MNG241
mng-umap@100
0.827