Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG690

07057aa6-b17b-5d3a-9343-271eb5ecb651

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • HEDGEHOG_SIGNALING+0.455
  • APICAL_SURFACE+0.305
  • KRAS_SIGNALING_DN+0.294
  • WNT_BETA_CATENIN_SIGNALING+0.271
  • MYOGENESIS+0.217
  • INTERFERON_ALPHA_RESPONSE+0.199
  • COAGULATION+0.196
  • INTERFERON_GAMMA_RESPONSE+0.181
  • ANGIOGENESIS+0.153
  • KRAS_SIGNALING_UP+0.152

Top 10 suppressed

  • OXIDATIVE_PHOSPHORYLATION-0.666
  • MYC_TARGETS_V1-0.648
  • MYC_TARGETS_V2-0.546
  • PROTEIN_SECRETION-0.545
  • MTORC1_SIGNALING-0.540
  • UNFOLDED_PROTEIN_RESPONSE-0.495
  • DNA_REPAIR-0.492
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.487
  • E2F_TARGETS-0.453
  • CHOLESTEROL_HOMEOSTASIS-0.449

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

5 twins match this tumor's tissue · 5 come from a different tissue of origin ← cross-tissue dominant

#SampleCancer typeSubtypecos similarity
1C3N-03890
lung-landscapes@6
cohortA10.917
2SRR1489155
brain-umap@2
GTEX0.915
3SRR6013548
lung-landscapes@6
cohortA10.911
4SRR1390582
brain-umap@2
GTEX0.910
5TCGA-75-7025-01A-12R-1949-07
lung-landscapes@6
cohortA10.906
6SRR1338301
brain-umap@2
GTEX0.906
7BS_YZ2Z1Q6Y
brain-umap@2
pilocytic astrocytoma0.904
8SRR1355613
brain-umap@2
GTEX0.904
920040065.TNBC
breast-umap@18
D0.903
10SRR650130
bladder-landscape@3
0.899