Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR12202410

07728e00-6c00-58b1-9139-c2a072e36842

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_ALPHA_RESPONSE+0.400
  • WNT_BETA_CATENIN_SIGNALING+0.370
  • HEDGEHOG_SIGNALING+0.300
  • INTERFERON_GAMMA_RESPONSE+0.300
  • PANCREAS_BETA_CELLS+0.250
  • KRAS_SIGNALING_DN+0.210
  • IL6_JAK_STAT3_SIGNALING+0.200
  • TNFA_SIGNALING_VIA_NFKB+0.200
  • HYPOXIA+0.140
  • P53_PATHWAY+0.110

Top 10 suppressed

  • PROTEIN_SECRETION-0.530
  • MYC_TARGETS_V1-0.420
  • OXIDATIVE_PHOSPHORYLATION-0.370
  • ANDROGEN_RESPONSE-0.350
  • UNFOLDED_PROTEIN_RESPONSE-0.310
  • MTORC1_SIGNALING-0.300
  • ADIPOGENESIS-0.290
  • ANGIOGENESIS-0.260
  • E2F_TARGETS-0.250
  • FATTY_ACID_METABOLISM-0.250

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1R186
bladder-landscape@3
0.818
2SRR12202413
bladder-landscape@3
0.813
3TCGA-LD-A7W5-01A-22R-A352-07
breast-umap@18
A0.808
4002260fb-3015-4876-b8fd-edffd7fc95e8
colon-landscapes@1
0.798
5SRR8613711
breast-umap@18
D0.763
6ERR2598151
medullo-epn-umap@date-based
fetalfetal0.760
7SRR2774280
melanoma-umap@29
0.758
8BS_G5QBBHDV
brain-umap@2
low-grade glioma0.749
9SRR13311155
bladder-landscape@3
0.749
10GSM6454742
breast-umap@18
D0.743