Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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307caf6a-9f70-5e84-b498-28057076a10e

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • ESTROGEN_RESPONSE_EARLY+0.300
  • PROTEIN_SECRETION+0.300
  • UV_RESPONSE_DN+0.300
  • WNT_BETA_CATENIN_SIGNALING+0.300
  • ANDROGEN_RESPONSE+0.200
  • BILE_ACID_METABOLISM+0.200
  • ESTROGEN_RESPONSE_LATE+0.200
  • TGF_BETA_SIGNALING+0.200
  • HEDGEHOG_SIGNALING+0.100
  • ANGIOGENESIS+0.000

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.500
  • E2F_TARGETS-0.400
  • IL6_JAK_STAT3_SIGNALING-0.400
  • INFLAMMATORY_RESPONSE-0.400
  • COMPLEMENT-0.300
  • G2M_CHECKPOINT-0.300
  • GLYCOLYSIS-0.300
  • INTERFERON_GAMMA_RESPONSE-0.300
  • IL2_STAT5_SIGNALING-0.200
  • KRAS_SIGNALING_UP-0.200

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
120030017.LumA
breast-umap@18
B0.859
2TCGA-A8-A09B-01A-11R-A00Z-07
breast-umap@18
B0.816
3TCGA-E2-A1IL-01A-11R-A14D-07
breast-umap@18
B0.795
4TCGA-BH-A0DO-01B-11R-A12D-07
breast-umap@18
A0.794
5TCGA-D8-A27P-01A-11R-A16F-07
breast-umap@18
B0.788
6TCGA-AN-A0XT-01A-11R-A109-07
breast-umap@18
B0.783
7SRR25617895
breast-umap@18
B0.783
8BSR_18_0092_S48
breast-umap@18
A0.778
92bd0477f-40af-4969-9291-c05ab3d55268
melanoma-umap@29
0.776
10ULC0569T_S27
lung-landscapes@6
cohortA10.776