Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

SRR8518323

· E

364645a6-d5ae-5c30-9e4d-edebca4ccfe5

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
E
subtype
E

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V2+0.690
  • E2F_TARGETS+0.660
  • MYC_TARGETS_V1+0.610
  • G2M_CHECKPOINT+0.570
  • INTERFERON_ALPHA_RESPONSE+0.480
  • OXIDATIVE_PHOSPHORYLATION+0.380
  • DNA_REPAIR+0.370
  • MTORC1_SIGNALING+0.360
  • INTERFERON_GAMMA_RESPONSE+0.340
  • UNFOLDED_PROTEIN_RESPONSE+0.280

Top 10 suppressed

  • UV_RESPONSE_DN-0.500
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.480
  • ANGIOGENESIS-0.470
  • HEDGEHOG_SIGNALING-0.450
  • APICAL_SURFACE-0.380
  • TGF_BETA_SIGNALING-0.380
  • MYOGENESIS-0.370
  • WNT_BETA_CATENIN_SIGNALING-0.370
  • APICAL_JUNCTION-0.330
  • NOTCH_SIGNALING-0.330

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-AR-A0TU-01A-31R-A109-07
breast-umap@18
E0.926
2SRR8518289
breast-umap@18
E0.920
3TCGA-A2-A4S3-01A-21R-A266-07
breast-umap@18
B0.919
4SRR8613729
breast-umap@18
E0.913
5SRR8518297
breast-umap@18
E0.908
620020093.Her2HRneg
breast-umap@18
E0.902
7TCGA-C8-A12U-01A-11R-A115-07
breast-umap@18
B0.900
8TCGA-58-A46M-01A-11R-A24H-07
lung-landscapes@6
cohortSQ20.896
958c2404d-b213-4a7f-a8fc-11081a88091b
colon-landscapes@1
0.896
10SRR8518360
breast-umap@18
E0.895