Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.

BS_FAQQ0GCQ

Ganglioglioma

36467048-757a-596f-8f6e-4e193063a503

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Ganglioglioma
cancer_type_detailed
subtype
cancer_type
Ganglioglioma
overall_survival_months
25.689881734559787
age_years
19.855
sex
Female

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

No GSVA scores available for this sample.

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

1 twin match this tumor's tissue · 9 come from a different tissue of origin ← cross-tissue dominant

#SampleCancer typeSubtypecos similarity
1BS_55JW3HFM
brain-umap@2
Ganglioglioma0.911
2BS_X91K8KMG
brain-umap@2
pilocytic astrocytoma0.893
3BS_MF9X3PKH
brain-umap@2
low-grade glioma0.888
4BS_HX0S30NE
brain-umap@2
pilocytic astrocytoma0.887
5BS_Z7Y2466H
brain-umap@2
pilocytic astrocytoma0.884
6BS_E94QRJDW
brain-umap@2
low-grade glioma0.884
7BS_F8N6CFQE
brain-umap@2
low-grade glioma0.875
8BS_7Z93ZYMS
brain-umap@2
pilocytic astrocytoma0.871
9BS_014EVM2D
brain-umap@2
low-grade glioma0.871
10ERR2598287
medullo-epn-umap@date-based
fetalfetal0.870

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 35 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
ALLOGRAFT_REJECTION0.581Idelalisib— uncovered
INTERFERON_GAMMA_RESPONSE0.560Idelalisib— uncovered
IL6_JAK_STAT3_SIGNALING0.541Inavolisib— uncovered
INTERFERON_ALPHA_RESPONSE0.515Inavolisib— uncovered
INFLAMMATORY_RESPONSE0.507Idelalisib— uncovered
ANDROGEN_RESPONSE0.443Inavolisib— uncovered
COAGULATION0.430Binimetinib— uncovered
COMPLEMENT0.429Inavolisib— uncovered
TNFA_SIGNALING_VIA_NFKB0.427Inavolisib— uncovered
KRAS_SIGNALING_UP0.402Inavolisib— uncovered
ANGIOGENESIS0.378Remibrutinib— uncovered
CHOLESTEROL_HOMEOSTASIS0.364Remibrutinib— uncovered
IL2_STAT5_SIGNALING0.346Idelalisib— uncovered
P53_PATHWAY0.344Idelalisib— uncovered
APICAL_SURFACE0.313Temsirolimus— uncovered
PROTEIN_SECRETION0.295Remibrutinib— uncovered
APOPTOSIS0.271Idelalisib— uncovered
PANCREAS_BETA_CELLS0.252Cobimetinib— uncovered
HEDGEHOG_SIGNALING0.235Inavolisib— uncovered
ESTROGEN_RESPONSE_EARLY0.219Inavolisib— uncovered