Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

SRR8613704

· A

37841291-a74c-5f3a-87f9-535e454a589b

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
A
subtype
A

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.460
  • ALLOGRAFT_REJECTION+0.450
  • UV_RESPONSE_DN+0.430
  • TGF_BETA_SIGNALING+0.340
  • ANGIOGENESIS+0.320
  • KRAS_SIGNALING_UP+0.310
  • IL6_JAK_STAT3_SIGNALING+0.300
  • INFLAMMATORY_RESPONSE+0.300
  • COMPLEMENT+0.270
  • INTERFERON_GAMMA_RESPONSE+0.230

Top 10 suppressed

  • MYC_TARGETS_V2-0.560
  • ESTROGEN_RESPONSE_LATE-0.410
  • OXIDATIVE_PHOSPHORYLATION-0.410
  • ESTROGEN_RESPONSE_EARLY-0.380
  • GLYCOLYSIS-0.350
  • MYC_TARGETS_V1-0.350
  • CHOLESTEROL_HOMEOSTASIS-0.340
  • MTORC1_SIGNALING-0.330
  • UV_RESPONSE_UP-0.330
  • ADIPOGENESIS-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR8518405
breast-umap@18
A0.871
2AUR-AE6X-TTP1-A-1-0-R-A741-41
breast-umap@18
D0.864
3C3L-02957
lung-landscapes@6
cohortMD20.850
4SRR4195664
colon-landscapes@1
0.848
5s0122308
melanoma-umap@29
0.844
6023160e4-1d9a-499c-9bfa-1b3aacf284f2
colon-landscapes@1
0.841
7AUR-AG12-TTP1-A-1-0-R-A741-41
breast-umap@18
A0.840
8ad478846-0a75-4081-ac09-37ee5415d9b4
colon-landscapes@1
0.840
9TCGA-CR-7382-01A-11R-2132-07
head-neck@1
0.832
1086db93b2-14b0-4094-bd69-222582df130c
colon-landscapes@1
0.831