MDT-AP-1338
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- os_event
- true
- age_years
- 11
- sex
- M
- new_clusters
- C2
- umap1_2d
- 2.241596956
- umap2_2d
- 0.611757127
- umap1_3d
- -0.672344785
- umap2_3d
- -1.536779422
- umap3_3d
- -0.5009092
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- MYC_TARGETS_V2+0.640
- MYC_TARGETS_V1+0.400
- KRAS_SIGNALING_DN+0.350
- PANCREAS_BETA_CELLS+0.250
- MTORC1_SIGNALING+0.120
- ESTROGEN_RESPONSE_LATE+0.110
- E2F_TARGETS+0.090
- OXIDATIVE_PHOSPHORYLATION+0.090
- MYOGENESIS+0.060
- UNFOLDED_PROTEIN_RESPONSE+0.060
Top 10 suppressed
- PROTEIN_SECRETION-0.440
- MITOTIC_SPINDLE-0.430
- TGF_BETA_SIGNALING-0.360
- INTERFERON_GAMMA_RESPONSE-0.330
- NOTCH_SIGNALING-0.330
- UV_RESPONSE_DN-0.330
- COMPLEMENT-0.320
- PI3K_AKT_MTOR_SIGNALING-0.290
- EPITHELIAL_MESENCHYMAL_TRANSITION-0.240
- TNFA_SIGNALING_VIA_NFKB-0.240
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
10 twins match this tumor's tissue · 0 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | MDT-AP-0412 | Med | Medulloblastoma | 0.827 |
| 2 | 43c87798-5762-42c1-b7d8-47fc126fc2d3 | — | — | 0.824 |
| 3 | MDT-AP-2281 | Med | Medulloblastoma | 0.797 |
| 4 | MDT-AP-2286 | Med | Medulloblastoma | 0.797 |
| 5 | TCGA-E2-A574-01A-11R-A29R-07 | — | E | 0.790 |
| 6 | MDT-AP-0182 | Med | Medulloblastoma | 0.783 |
| 7 | MDT-AP-2069 | Med | Medulloblastoma | 0.760 |
| 8 | TCGA-77-A5GA-01A-11R-A27Q-07 | — | cohortSQ2 | 0.752 |
| 9 | SRR9879286 | — | cohortSQ2 | 0.749 |
| 10 | TCGA-E2-A576-01A-11R-A31O-07 | — | B | 0.749 |