Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR12475140

3bfa9f3b-a412-5336-a826-75dc4cb183fc

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.570
  • INFLAMMATORY_RESPONSE+0.520
  • ALLOGRAFT_REJECTION+0.510
  • ANGIOGENESIS+0.510
  • INTERFERON_GAMMA_RESPONSE+0.480
  • TNFA_SIGNALING_VIA_NFKB+0.470
  • INTERFERON_ALPHA_RESPONSE+0.440
  • IL6_JAK_STAT3_SIGNALING+0.390
  • COMPLEMENT+0.320
  • UV_RESPONSE_DN+0.310

Top 10 suppressed

  • OXIDATIVE_PHOSPHORYLATION-0.540
  • MYC_TARGETS_V2-0.450
  • PEROXISOME-0.400
  • BILE_ACID_METABOLISM-0.380
  • FATTY_ACID_METABOLISM-0.370
  • ADIPOGENESIS-0.350
  • DNA_REPAIR-0.320
  • GLYCOLYSIS-0.320
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.320
  • MYC_TARGETS_V1-0.310

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

6 twins match this tumor's tissue · 4 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1767fc312-2c66-43f7-b78e-bf79e03e3a0a
colon-landscapes@1
0.903
2SRR6013514
lung-landscapes@6
cohortMD20.893
3SRR23303766
bladder-landscape@3
0.887
4SRR1335446
brain-umap@2
GTEX0.887
5SRR607445
brain-umap@2
GTEX0.884
6SRR821602
brain-umap@2
GTEX0.882
7c56e13bb-f1b0-4ee3-85c1-807c7c3bcef9
colon-landscapes@1
0.882
8ec054d40-e5b8-496a-8c99-5e7f88f2cf37
colon-landscapes@1
0.881
9MBCProject_1819_T2A_RNA
breast-umap@18
A0.876
10SRR818270
brain-umap@2
GTEX0.876