Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG610

3e8df3ae-aef0-5648-ac33-cf23c283cc9e

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • CHOLESTEROL_HOMEOSTASIS+0.449
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.401
  • TNFA_SIGNALING_VIA_NFKB+0.378
  • HYPOXIA+0.347
  • ESTROGEN_RESPONSE_EARLY+0.326
  • PEROXISOME+0.324
  • ESTROGEN_RESPONSE_LATE+0.314
  • MYC_TARGETS_V2+0.314
  • P53_PATHWAY+0.309
  • APOPTOSIS+0.300

Top 10 suppressed

  • G2M_CHECKPOINT-0.394
  • E2F_TARGETS-0.327
  • PROTEIN_SECRETION-0.300
  • MITOTIC_SPINDLE-0.278
  • UV_RESPONSE_DN-0.227
  • SPERMATOGENESIS-0.172
  • KRAS_SIGNALING_UP-0.115
  • NOTCH_SIGNALING-0.107
  • PI3K_AKT_MTOR_SIGNALING-0.050
  • WNT_BETA_CATENIN_SIGNALING-0.028

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

4 twins match this tumor's tissue · 6 come from a different tissue of origin ← cross-tissue dominant

#SampleCancer typeSubtypecos similarity
1131e315e-6653-4199-b653-42b81644dad9
colon-landscapes@1
0.829
2SRR1347688
brain-umap@2
GTEX0.828
3SRR1465917
brain-umap@2
GTEX0.821
4BS_YCREDZTJ
brain-umap@2
low-grade glioma0.799
5MNG413
mng-umap@100
0.798
6SRR1328487
brain-umap@2
GTEX0.798
7SRR1488349
brain-umap@2
GTEX0.796
8SRR818348
brain-umap@2
GTEX0.795
9AUR-AFEC-TTM4-A-1-1-R-A742-41
breast-umap@18
C0.794
10TCGA-E9-A6HE-01A-11R-A31O-07
breast-umap@18
B0.792