Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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20070115.Her2HRneg

· E

3f9f1664-3d74-5e53-a80a-6f8eef788d5b

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
E
subtype
E

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.470
  • APICAL_JUNCTION+0.400
  • APICAL_SURFACE+0.370
  • MYOGENESIS+0.330
  • WNT_BETA_CATENIN_SIGNALING+0.310
  • COAGULATION+0.290
  • NOTCH_SIGNALING+0.280
  • UV_RESPONSE_DN+0.280
  • CHOLESTEROL_HOMEOSTASIS+0.270
  • PANCREAS_BETA_CELLS+0.200

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.570
  • INTERFERON_GAMMA_RESPONSE-0.460
  • ALLOGRAFT_REJECTION-0.310
  • MYC_TARGETS_V2-0.280
  • DNA_REPAIR-0.220
  • INFLAMMATORY_RESPONSE-0.180
  • OXIDATIVE_PHOSPHORYLATION-0.180
  • IL2_STAT5_SIGNALING-0.140
  • HEDGEHOG_SIGNALING-0.130
  • COMPLEMENT-0.100

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-33-4547-01A-01R-1201-07
lung-landscapes@6
cohortSQ10.767
2SRR8613758
breast-umap@18
C0.764
3SRR8518427
breast-umap@18
E0.760
4SRR8613779
breast-umap@18
D0.731
5SRR9879274
lung-landscapes@6
cohortSQ10.715
6SRR8518326
breast-umap@18
E0.713
7TCGA-AO-A0J5-01A-11R-A034-07
breast-umap@18
A0.704
8TCGA-BH-A0HY-01A-11R-A056-07
breast-umap@18
C0.703
9SRR8613703
breast-umap@18
D0.701
10TCGA-BL-A13J-01A-11R-A10U-07
bladder-landscape@3
0.698