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MDT-AP-3274

Med · Medulloblastoma

57a49a57-771f-5672-82fa-92bf6fe43d56

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
age_years
1.1
sex
M
new_clusters
S3
umap1_2d
-2.919360093
umap2_2d
-7.701068764
umap1_3d
-2.984366164
umap2_3d
-3.321222186
umap3_3d
7.903899261
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_ALPHA_RESPONSE+0.470
  • ALLOGRAFT_REJECTION+0.460
  • INTERFERON_GAMMA_RESPONSE+0.460
  • IL6_JAK_STAT3_SIGNALING+0.440
  • INFLAMMATORY_RESPONSE+0.420
  • UV_RESPONSE_DN+0.420
  • COMPLEMENT+0.380
  • KRAS_SIGNALING_UP+0.350
  • PROTEIN_SECRETION+0.330
  • TNFA_SIGNALING_VIA_NFKB+0.330

Top 10 suppressed

  • E2F_TARGETS-0.670
  • G2M_CHECKPOINT-0.570
  • MYC_TARGETS_V2-0.570
  • MYC_TARGETS_V1-0.510
  • DNA_REPAIR-0.470
  • UNFOLDED_PROTEIN_RESPONSE-0.270
  • GLYCOLYSIS-0.240
  • SPERMATOGENESIS-0.240
  • MTORC1_SIGNALING-0.220
  • MITOTIC_SPINDLE-0.160

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1BS_YVMEEBKC
brain-umap@2
pilocytic astrocytoma0.910
2MDT-AP-3282
medullo-epn-umap@date-based
MedMedulloblastoma0.895
3TCGA-AC-A2FB-01A-11R-A17B-07
breast-umap@18
A0.894
4TCGA-49-6744-01A-11R-1858-07
lung-landscapes@6
cohortA10.889
5TCGA-91-7771-01A-11R-2170-07
lung-landscapes@6
cohortA20.884
6SRR17866835
colon-landscapes@1
0.882
7BS_C6SKJG3N
brain-umap@2
pilocytic astrocytoma0.880
8TCGA-A7-A0CG-01A-12R-A056-07
breast-umap@18
A0.880
9TCGA-AC-A2FO-01A-11R-A180-07
breast-umap@18
A0.880
102eaa09cd-8e3e-4de9-ab96-7a290d780a01
colon-landscapes@1
0.879