MDT-AP-3280
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- age_years
- 0.6
- sex
- M
- new_clusters
- S3
- umap1_2d
- -2.553482813
- umap2_2d
- -7.872899069
- umap1_3d
- -3.317945938
- umap2_3d
- -3.194426467
- umap3_3d
- 7.617368888
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- INTERFERON_ALPHA_RESPONSE+0.560
- INTERFERON_GAMMA_RESPONSE+0.510
- UV_RESPONSE_DN+0.480
- INFLAMMATORY_RESPONSE+0.430
- ALLOGRAFT_REJECTION+0.420
- IL6_JAK_STAT3_SIGNALING+0.420
- EPITHELIAL_MESENCHYMAL_TRANSITION+0.390
- PROTEIN_SECRETION+0.390
- ANDROGEN_RESPONSE+0.360
- NOTCH_SIGNALING+0.360
Top 10 suppressed
- MYC_TARGETS_V2-0.310
- DNA_REPAIR-0.280
- PANCREAS_BETA_CELLS-0.260
- SPERMATOGENESIS-0.200
- MYC_TARGETS_V1-0.190
- KRAS_SIGNALING_DN-0.160
- OXIDATIVE_PHOSPHORYLATION-0.120
- REACTIVE_OXYGEN_SPECIES_PATHWAY-0.040
- UV_RESPONSE_UP-0.030
- E2F_TARGETS-0.020
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
6 twins match this tumor's tissue · 4 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | SJEPD032296_D1.RNA-Seq | EPN | Anaplastic EPN | 0.901 |
| 2 | BS_0SCXXM6N | low-grade glioma | — | 0.901 |
| 3 | efe57fc7-7cf4-432b-86ff-9fd2d1a37b5e | — | — | 0.896 |
| 4 | BS_VP5Y45Z7 | pilocytic astrocytoma | — | 0.890 |
| 5 | MDT-AP-2029 | Med | Medulloblastoma | 0.887 |
| 6 | MDT-AP-3338 | Med | Medulloblastoma | 0.885 |
| 7 | BS_014EVM2D | low-grade glioma | — | 0.881 |
| 8 | TCGA-86-8075-01A-11R-2241-07 | — | cohortA1 | 0.876 |
| 9 | TCGA-FD-A3B8-01A-31R-A20F-07 | — | — | 0.874 |
| 10 | MNG664 | — | — | 0.870 |