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SJEPD032296_D1.RNA-Seq

EPN · Anaplastic EPN

829250ab-826c-5d64-b63f-fc3356bbd79b

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
EPN
cancer_type_detailed
subtype
Anaplastic EPN
cancer_type
EPN
subtype
Anaplastic EPN
age_years
1.67
e1_e2
E2
umap1_2d
-6.079096031
umap2_2d
1.411888363
umap1_3d
-0.596117697
umap2_3d
3.748657282
umap3_3d
0.074686979
dataset
EPN-StJude

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • IL6_JAK_STAT3_SIGNALING+0.520
  • TNFA_SIGNALING_VIA_NFKB+0.500
  • INFLAMMATORY_RESPONSE+0.490
  • INTERFERON_GAMMA_RESPONSE+0.470
  • UV_RESPONSE_DN+0.400
  • IL2_STAT5_SIGNALING+0.380
  • ALLOGRAFT_REJECTION+0.370
  • COMPLEMENT+0.350
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.350
  • TGF_BETA_SIGNALING+0.350

Top 10 suppressed

  • PANCREAS_BETA_CELLS-0.480
  • MYC_TARGETS_V2-0.350
  • OXIDATIVE_PHOSPHORYLATION-0.350
  • E2F_TARGETS-0.280
  • DNA_REPAIR-0.230
  • KRAS_SIGNALING_DN-0.200
  • SPERMATOGENESIS-0.140
  • G2M_CHECKPOINT-0.130
  • MYC_TARGETS_V1-0.130
  • ADIPOGENESIS-0.120

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-3280
medullo-epn-umap@date-based
MedMedulloblastoma0.901
2efe57fc7-7cf4-432b-86ff-9fd2d1a37b5e
melanoma-umap@29
0.900
3SAMN03290930
melanoma-umap@29
0.893
4SRR934741
brain-umap@2
0.892
5TCGA-A8-A096-01A-11R-A00Z-07
breast-umap@18
B0.890
6TCGA-63-A5MN-01A-22R-A27Q-07
lung-landscapes@6
cohortA10.886
753933_S131
lung-landscapes@6
cohortA10.882
8SJEPD031078_D1.RNA-Seq
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.871
9TCGA-86-8075-01A-11R-2241-07
lung-landscapes@6
cohortA10.869
10TCGA-50-5939-01A-11R-1628-07
lung-landscapes@6
cohortA10.868