BS_4W68NV3M
medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- medulloblastoma
- cancer_type_detailed
- —
- subtype
- —
- cancer_type
- medulloblastoma
- overall_survival_months
- 53.810775295663596
- age_years
- 7.559
- sex
- Male
GSVA pathway preview (0 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
8 twins match this tumor's tissue · 2 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | BS_QRDT19KS | medulloblastoma | — | 0.981 |
| 2 | BS_A87NPZAP | medulloblastoma | — | 0.960 |
| 3 | BS_1TWCV047 | Embryonal tumors | — | 0.960 |
| 4 | BS_W311713R | medulloblastoma | — | 0.958 |
| 5 | BS_NZ71XCG3 | medulloblastoma | — | 0.957 |
| 6 | SRR650166 | — | — | 0.955 |
| 7 | BS_S1M423AB | Embryonal tumors | — | 0.951 |
| 8 | BS_77317DY4 | medulloblastoma | — | 0.947 |
| 9 | C3N-03886 | — | cohortMD1 | 0.946 |
| 10 | BS_3NWQXPQV | medulloblastoma | — | 0.945 |
Per-pathway drug coverage
For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.
0 of 8 elevated pathways have at least one drug that meaningfully reverses them.
| Pathway (elevated) | tumor score | Best drug | reversal magnitude |
|---|---|---|---|
| E2F_TARGETS | 0.243 | Inavolisib | — uncovered |
| G2M_CHECKPOINT | 0.233 | Inavolisib | — uncovered |
| SPERMATOGENESIS | 0.167 | Inavolisib | — uncovered |
| MITOTIC_SPINDLE | 0.164 | Inavolisib | — uncovered |
| WNT_BETA_CATENIN_SIGNALING | 0.103 | Inavolisib | — uncovered |
| DNA_REPAIR | 0.080 | Idelalisib | — uncovered |
| PANCREAS_BETA_CELLS | 0.029 | Cobimetinib | — uncovered |
| MYC_TARGETS_V2 | 0.010 | Idelalisib | — uncovered |