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SRR6079994

7c936fa7-7ebe-59d2-82e2-bf567d7c5a04

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
sex
female

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

No GSVA scores available for this sample.

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

7 twins match this tumor's tissue · 3 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR1516074
bladder-landscape@3
0.845
2BS_V7BJM89K
brain-umap@2
low-grade glioma0.839
3MDT-AP-0373
medullo-epn-umap@date-based
MedMedulloblastoma0.830
4SRR1313097
breast-umap@18
A0.826
5TCGA-97-A4M1-01A-11R-A24X-07
lung-landscapes@6
cohortA10.821
6TCGA-OL-A5DA-01A-11R-A27Q-07
breast-umap@18
B0.816
7TCGA-55-8097-01A-11R-2241-07
lung-landscapes@6
cohortA10.816
8C3L-00444
lung-landscapes@6
cohortA10.815
9C3L-02958
lung-landscapes@6
cohortA10.813
10MDT-AP-1121
medullo-epn-umap@date-based
MedMedulloblastoma0.807

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 12 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
P53_PATHWAY0.250Idelalisib— uncovered
WNT_BETA_CATENIN_SIGNALING0.160Inavolisib— uncovered
KRAS_SIGNALING_DN0.140Remibrutinib— uncovered
MYOGENESIS0.130Inavolisib— uncovered
TGF_BETA_SIGNALING0.090Inavolisib— uncovered
PANCREAS_BETA_CELLS0.080Cobimetinib— uncovered
XENOBIOTIC_METABOLISM0.060Inavolisib— uncovered
COAGULATION0.020Binimetinib— uncovered
ESTROGEN_RESPONSE_EARLY0.020Inavolisib— uncovered
INFLAMMATORY_RESPONSE0.020Idelalisib— uncovered
BILE_ACID_METABOLISM0.010Inavolisib— uncovered
CHOLESTEROL_HOMEOSTASIS0.010Remibrutinib— uncovered