MDT-AP-0203
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- age_years
- 1.4
- sex
- F
- new_clusters
- C1
- umap1_2d
- 3.616174281
- umap2_2d
- 0.138998466
- umap1_3d
- 0.006669575
- umap2_3d
- -1.603445475
- umap3_3d
- -0.029991739
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- MYC_TARGETS_V1+0.600
- OXIDATIVE_PHOSPHORYLATION+0.530
- MYC_TARGETS_V2+0.490
- E2F_TARGETS+0.470
- G2M_CHECKPOINT+0.390
- MTORC1_SIGNALING+0.380
- ANGIOGENESIS+0.310
- EPITHELIAL_MESENCHYMAL_TRANSITION+0.310
- ADIPOGENESIS+0.280
- REACTIVE_OXYGEN_SPECIES_PATHWAY+0.270
Top 10 suppressed
- HEDGEHOG_SIGNALING-0.390
- NOTCH_SIGNALING-0.280
- WNT_BETA_CATENIN_SIGNALING-0.210
- APICAL_JUNCTION-0.190
- MITOTIC_SPINDLE-0.160
- PROTEIN_SECRETION-0.150
- UV_RESPONSE_DN-0.140
- ESTROGEN_RESPONSE_EARLY-0.100
- INTERFERON_ALPHA_RESPONSE-0.100
- IL6_JAK_STAT3_SIGNALING-0.070
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
10 twins match this tumor's tissue · 0 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | TCGA-18-3421-01A-01R-0980-07 | — | cohortSQ1 | 0.863 |
| 2 | MDT-AP-2494 | Med | Medulloblastoma | 0.853 |
| 3 | BS_R439VVPK | Med | Medulloblastoma | 0.840 |
| 4 | TCGA-18-3411-01A-01R-0980-07 | — | cohortSQ2 | 0.838 |
| 5 | MDT-AP-0549 | Med | Medulloblastoma | 0.834 |
| 6 | MDT-AP-0538 | Med | Medulloblastoma | 0.833 |
| 7 | TCGA-66-2795-01A-02R-0980-07 | — | cohortSQ2 | 0.827 |
| 8 | SRR6013603 | — | cohortA3 | 0.827 |
| 9 | TCGA-PQ-A6FN-01A-11R-A31N-07 | — | — | 0.813 |
| 10 | MNG158 | — | — | 0.811 |