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MDT-AP-2086

Med · Medulloblastoma

985f7deb-bcb3-50c8-81ae-dff12eacb438

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
age_years
0.5
sex
F
new_clusters
S3
umap1_2d
-1.086596052
umap2_2d
-7.613971415
umap1_3d
-3.526799494
umap2_3d
-3.21017203
umap3_3d
6.101014765
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • TNFA_SIGNALING_VIA_NFKB+0.590
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.560
  • IL6_JAK_STAT3_SIGNALING+0.510
  • INFLAMMATORY_RESPONSE+0.500
  • INTERFERON_GAMMA_RESPONSE+0.500
  • ALLOGRAFT_REJECTION+0.490
  • INTERFERON_ALPHA_RESPONSE+0.470
  • APICAL_SURFACE+0.430
  • E2F_TARGETS+0.410
  • NOTCH_SIGNALING+0.410

Top 10 suppressed

  • OXIDATIVE_PHOSPHORYLATION-0.200
  • PEROXISOME-0.200
  • SPERMATOGENESIS-0.200
  • HEME_METABOLISM-0.140
  • PROTEIN_SECRETION-0.130
  • BILE_ACID_METABOLISM-0.080
  • DNA_REPAIR-0.070
  • KRAS_SIGNALING_DN-0.070
  • ADIPOGENESIS-0.060
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.050

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-1404
medullo-epn-umap@date-based
MedMedulloblastoma0.921
2BS_J1AB8PMA
medullo-epn-umap@date-based
MedMedulloblastoma0.919
3MDT-AP-2040
medullo-epn-umap@date-based
MedMedulloblastoma0.902
4F547C7BB-DBF1-4805-A0EA-D8BC36606032
brain-umap@2
0.901
5AUR-AFUI-TTP1-A-1-0-R-A743-41
breast-umap@18
C0.895
6SRR10899973
melanoma-umap@29
0.890
7SRR10900575
melanoma-umap@29
0.889
8MDT-AP-0205
medullo-epn-umap@date-based
MedMedulloblastoma0.889
9TCGA-FT-A61P-01A-11R-A30C-07
bladder-landscape@3
0.886
10R303
bladder-landscape@3
0.882