Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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9b1e37df-4fcc-5775-9739-dedbf58847f6

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
age_years
74.4421629021218

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_ALPHA_RESPONSE+0.430
  • E2F_TARGETS+0.370
  • G2M_CHECKPOINT+0.350
  • PANCREAS_BETA_CELLS+0.340
  • ANGIOGENESIS+0.230
  • INTERFERON_GAMMA_RESPONSE+0.210
  • MYC_TARGETS_V1+0.210
  • KRAS_SIGNALING_DN+0.180
  • MITOTIC_SPINDLE+0.160
  • SPERMATOGENESIS+0.160

Top 10 suppressed

  • TGF_BETA_SIGNALING-0.350
  • HEDGEHOG_SIGNALING-0.300
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.290
  • ALLOGRAFT_REJECTION-0.270
  • APICAL_SURFACE-0.270
  • UNFOLDED_PROTEIN_RESPONSE-0.250
  • HYPOXIA-0.210
  • NOTCH_SIGNALING-0.200
  • PROTEIN_SECRETION-0.190
  • UV_RESPONSE_DN-0.180

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR12202474
bladder-landscape@3
0.671
2aa786193-fb52-46b2-a71a-1b94cbf47810
colon-landscapes@1
0.665
3TCGA-BA-A6DE-01A-22R-A31N-07
head-neck@1
0.663
4BS_YEW22W35
brain-umap@2
high-grade glioma0.657
5SRR8518294
breast-umap@18
E0.644
6TCGA-EW-A1PC-01B-11R-A21T-07
breast-umap@18
C0.644
7SRR25617935
breast-umap@18
E0.642
8R219
bladder-landscape@3
0.634
9ULC0564T_S96
lung-landscapes@6
cohortA10.627
10C3L-01000
lung-landscapes@6
cohortA40.625