Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

SAMN03290931

9de65aa6-8f2b-50ec-a69f-4969f212509f

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V1+0.500
  • E2F_TARGETS+0.400
  • MYC_TARGETS_V2+0.400
  • UNFOLDED_PROTEIN_RESPONSE+0.400
  • G2M_CHECKPOINT+0.300
  • MTORC1_SIGNALING+0.300
  • OXIDATIVE_PHOSPHORYLATION+0.300
  • PROTEIN_SECRETION+0.300
  • DNA_REPAIR+0.200
  • GLYCOLYSIS+0.200

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.600
  • INTERFERON_GAMMA_RESPONSE-0.500
  • ALLOGRAFT_REJECTION-0.400
  • COAGULATION-0.400
  • COMPLEMENT-0.400
  • IL6_JAK_STAT3_SIGNALING-0.400
  • INFLAMMATORY_RESPONSE-0.400
  • APICAL_SURFACE-0.300
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.300
  • IL2_STAT5_SIGNALING-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR10899994
melanoma-umap@29
0.920
2AUR-AFR3-TTM1-A-1-1-R-A743-41
breast-umap@18
C0.917
3SAMN03290927
melanoma-umap@29
0.912
4004064de-0e10-491d-b3d8-bc628a8f70a8
melanoma-umap@29
0.909
5BS_JTMXAMB7
brain-umap@2
medulloblastoma0.909
620120209.TNBC
breast-umap@18
E0.909
7236350e9-8964-42ae-8880-d2f2281ff993
melanoma-umap@29
0.905
8BS_G23JJAZY
medullo-epn-umap@date-based
EPNSupratentorial EPN0.901
9C3L-02649
lung-landscapes@6
cohortMD10.900
104e2a5058-c190-49de-97f4-0ba7be7ebfe8
colon-landscapes@1
0.897