Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.400
  • G2M_CHECKPOINT+0.400
  • MITOTIC_SPINDLE+0.400
  • UNFOLDED_PROTEIN_RESPONSE+0.400
  • GLYCOLYSIS+0.300
  • OXIDATIVE_PHOSPHORYLATION+0.300
  • PROTEIN_SECRETION+0.300
  • SPERMATOGENESIS+0.300
  • ADIPOGENESIS+0.200
  • MTORC1_SIGNALING+0.200

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.600
  • INTERFERON_GAMMA_RESPONSE-0.600
  • IL6_JAK_STAT3_SIGNALING-0.500
  • INFLAMMATORY_RESPONSE-0.500
  • INTERFERON_ALPHA_RESPONSE-0.500
  • COMPLEMENT-0.400
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.400
  • KRAS_SIGNALING_UP-0.400
  • TNFA_SIGNALING_VIA_NFKB-0.400
  • APOPTOSIS-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG797
mng-umap@100
0.902
2MNG1195
mng-umap@100
0.889
3SRR5088859
melanoma-umap@29
0.887
4236350e9-8964-42ae-8880-d2f2281ff993
melanoma-umap@29
0.878
5SAMN03290931
melanoma-umap@29
0.877
620120209.TNBC
breast-umap@18
E0.869
7R6
bladder-landscape@3
0.865
8MDT-AP-2956
medullo-epn-umap@date-based
MedMedulloblastoma0.862
949319954-0844-4fbc-a931-df0e4cdbcb14
melanoma-umap@29
0.860
10C3L-02649
lung-landscapes@6
cohortMD10.859